General Physiology and Biophysics
An International Journal
November 2025
Volume 44, Issue 6, p. 439-538
Curcumin-chitosan microspheres inhibit epithelial cell PANoptosis: analysis of key PANoptosis gene distribution via single-cell RNA sequencing and in vivo validation in ulcerative colitis mice
Xinyou Pan, Qiaohong Zhu, Yanru Xiang, Jiaqi Liu, Chengdong Yu and Guodong Huang
Saponin of Rhizoma Polygonati inhibits neuronal apoptosis and ameliorates cognitive deficits in Alzheimer’s disease mice by modulating c-Abl/MST1 pathway
Changying Zhang, Xudong Tang and Shixing Wu
LncRNA SOX9-AS1 promotes the development of endometrial cancer by sponging miR-497-5p and upregulating E2F transcription factor
Baojin Zeng, Jingjing Lin, Xiuling Ren and Yali Cheng
Transcription factor SPI1 exacerbates the malignant progression of esophageal squamous cell carcinoma byactivating LAMA3 expression
Juan Qin, Yunxiang Tang, Rui Zhu, Xuqin Feng, Jun Bie, Qikun Lv and Yang Shu
LncRNA SOX2OT improves insulin resistance in type 2 diabetes with sleep disorders by activating IRS/PI3K/AKT and suppressing oxidative stress and inflammation through the miR-552-5p/SOX2 axis
Yalan Wang, Li Zheng, Jing Dai, Xiaoshi Yang, Feng Tang, Yan Li and Yu Lu
Role of SIRT1-HMGB1-NLRP3 inflammasome axis in the protective effects of trans-chalcone on myocardial ischemia and reperfusion injury
Xiuming Zhou, Juan Sun, Shouming Ren, Qifeng Shen, Qinghua Chi and Haijun Pang
DCAF1 promotes the growth and metastasis of pancreatic cancer cells by activating the PTEN/PI3K/Akt signaling pathway
Jiawei Wang, Yifeng Wu, Wenyi Xu and Qingqing Ruan
Paeonol attenuates oxidative stress and inflammation in experimental diabetic retinopathy by regulating the Nrf2/NF-κB signaling
Xiaoyu Li and Kehu Wu
© 2025 Institute of Molecular Physiology and Genetics, Slovak Academy of Sciences